Senior Human Resources Business Partner

MyOme’s mission is to provide clinically actionable genetic information to patients throughout their lives. We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation, and seamless digital tools for doctors and patients to order and access results. Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top-tier investors.

Position Overview:

MyOme is seeking a Senior Human Resources Business Partner (HRBP) to serve as a strategic and hands-on partner to our SVP of Corporate Operations, driving employee relations, HR policy, and performance management across all departments. This role will build core HRBP infrastructure from the ground up on a nimble HR team (including working in close partnership with our HR Manager, who leads Talent Acquisition, Onboarding, and Culture) to deliver a seamless employee experience and management. The ideal candidate would bring deep HRBP experience from within biotech or genomics, be comfortable helping to establish “right-sized” HR resources and playbooks; and move fluidly between advising leadership and rolling up their sleeves to execute. This person will also serve as an informal mentor, sharing HRBP frameworks and best practices with HR colleagues as MyOme's people function continues to mature.

What You'll Do:

Serve as a trusted, day-to-day HR advisor to managers and employees across all departments on employee relations, performance concerns, and workplace matters, building relationships that let you anticipate issues before they escalate

Partner with the SVP of Corporate Operations to translate business priorities into HR strategy and actionable people programs

Design, implement, and maintain HR policies and procedures that scale with a growing biotech organization, ensuring compliance with federal, state, and local employment law

Own performance management, succession planning, and promotion processes, right-sized for our stage

Independently investigate and resolve employee relations matters end-to-end — scoping, conducting the investigation, documenting findings, and recommending action with sound judgment and discretion

Build foundational HRBP infrastructure, including templates, workflows, and manager toolkits, in a lean, resource-conscious environment

Act as the primary point of escalation for leave management issues and related risk

Stay current on employment law changes — including updates from the DFEH/CRD, DOL, and EEOC — proactively flagging risk areas and advising leadership as regulations evolve

Provide guidance on adjacent HR functions, such as compensation strategy and benefits administration, as questions arise

Partner with the HR Manager to research and analyze HR trends and people metrics, such as turnover and engagement, to develop proactive strategies that improve employee relations outcomes

Promote a positive workplace culture aligned with company values, fostering engagement, collaboration, and employee well-being

Identify opportunities for continuous improvement in HR processes and implement best practices as the organization scales

Provide informal, ongoing HRBP coaching and knowledge-sharing to HR colleagues, helping build broader HR capability across the team

What You'll Ne ed:

5+ years of experience as an HR Business Partner or in a similar generalist, employee relations-focused HR role

Prior experience within biotech, genomics, or life sciences required, with familiarity with the compliance considerations and operating pace specific to the industry

Demonstrated experience independently managing employee relations matters with sound judgment and discretion

Working knowledge of federal and state employment law, particularly California

Experience designing or refining HR policies, performance management programs, or manager training within a growing organization

Comfort operating in a lean, resource-constrained environment, with the ability to build processes and infrastructure from scratch

Strong interpersonal and coaching skills, with the ability to build trust across all levels of the organization, from individual contributors to senior leadership

A collaborative, partnership-oriented mindset and a willingness to share knowledge and mentor colleagues newer to HRBP work

Excellent judgment and integrity when handling sensitive and confidential information

SHRM-CP, PHR, or similar HR certification a plus but not required

Location, Compensation, and Benefits:

Location: Hybrid, Menlo Park, CA (2–3 days onsite). Open to considering remote candidates within the U.S. for the right fit.

Compensation: Annual base salary range is $135,000 - $175,000, based on experience and biotech/genomics HRBP background

San Francisco Bay Area pay range

$135,000 — $175,000 USD

Benefits:

Comprehensive healthcare coverage (Health, Dental, and Vision)

401K

Unlimited PTO

Professional development opportunities

Company-sponsored off-sites and team meals during in-person meetings

Direct access to company leadership and the opportunity for career growth

Diversity, Inclusion, and Equal Opportunity:

MyOme values diversity in all forms. We believe that diverse perspectives drive better science and better patient outcomes. We are an Equal Opportunity Employer committed to creating an inclusive workplace that empowers every individual.

Why Work at MyOme?

Join us if you:

Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level

Enjoy rolling up your sleeves, taking initiative, and being empowered to lead

Value humility, transparency, and collaborative problem-solving

Thrive in fast-moving, dynamic environments with smart, driven teammates

Appreciate competitive compensation, meaningful equity, and excellent benefits

Learn More: myome.com